DUBLIN, Nov. 5, 2025 /PRNewswire/ -- Alkermes plc (Nasdaq: ALKS):

IRISH TAKEOVER PANEL

OPENING POSITION DISCLOSURE UNDER RULE 8.1(a) AND (b) OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER RULES, 2022 BY AN OFFEROR OR AN OFFEREE

1. KEY INFORMATION

        (a)                     Full name of discloser:                         Alkermes plc


        (b)                     Owner or controller of interests and
                                 short                                                   N/A
             positions disclosed, if different from
             1(a):



                                The naming of nominee or vehicle
             companies is insufficient. For a
             trust, the
             trustee(s), settlor and beneficiaries
             must
            be named.


        (c)                     Name of offeror/offeree in relation
                                 to whose                              
            Avadel
            relevant securities this form relates:                     Pharmaceuticals
                                                                       plc


                                Use a separate form for each offeror/
                                 offeree


        (d)                     Is the discloser the offeror or the
                                 offeree?                                       OFFEROR

    ---

        (e)                     Date position held:                             3 November
                                                                                        2025


                                The latest practicable date prior to
                                 the
            disclosure


        (f)                     In addition to the company in 1(c)
                                 above, is                                               N/A
             the discloser also making disclosures
             in
             respect of any other party to the
             offer?



                                If it is a cash offer or possible cash
                                 offer, state
            "N/A"

    ---

2. INTERESTS AND SHORT POSITIONS

If there are interests and positions to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2 for each additional class of relevant security.

Interests and short positions in the relevant securities of the offeror or offeree to which the disclosure relates (Note 1)

N/A

All interests and all short positions should be disclosed.

Details of options including rights to subscribe for new securities and any open stock-settled derivative positions (including traded options), or agreements to purchase or sell relevant securities, should be given on a Supplemental Form 8.

3. INTERESTS AND SHORT POSITIONS OF PERSONS ACTING
IN CONCERT WITH THE PARTY MAKING THE DISCLOSURE


              
                Details of any interests and short positions (including directors'
    and other employee options) of any person acting in concert with
    the party making the disclosure:



              Interests of J.P. Morgan (together with its members of staff under Rule
    3.3(b)(v) of Part A of the Irish Takeover Rules), financial advisors to
    Alkermes plc, but, for clarity, not held on behalf of Alkermes plc:


                                        Party                           Class of                     Number of              Percentage
                                              Relevant                           ordinary                      of total
                                              Security                           shares held                   issued share
                                                                                 at midnight                   capital
                                                                                 (ET) on                       (rounded)
                                                                                 3 November
                                                                                                        2025


                           55I, LLC                        Ordinary                                         53                 0.0001 %
                                              shares of
                                              US$0.01
                                              each


                           JPMorgan                        Ordinary                                     13,500                 0.0139 %
                Chase Bank,                     shares of
                National                        US$0.01
                Association                     each


                           TOTAL                                                                        13,553                 0.0139 %









              
                Details of any open stock-settled derivative positions (including traded
    options), or agreements to purchase or sell relevant securities, should
    be given on a Supplemental Form 8.

Ap11

4. OTHER INFORMATION

(a) Indemnity and other dealing arrangements


              
                Details of any indemnity or option arrangement, or any agreement
    or understanding, formal or informal, relating to relevant securities
    which may be an inducement to deal or refrain from dealing entered
    into by the party to the offer making the disclosure or any person
    acting in concert with it:





              
                Irrevocable commitments and letters of intent should not be included. If
    there are no such agreements, arrangements or understandings, state
    "none"






              
                None

(b) Agreements, arrangements or understandings
relating to options or derivatives


              
                Full details of any agreement, arrangement or understanding
    between the person disclosing and any other person relating to the
    voting rights of any relevant securities under any option referred
    to on this form or relating to the voting rights or future acquisition
    or disposal of any relevant securities to which any derivative
    referred to on this form is referenced. If none, this should be stated.





              
                None

(c) Attachments


              
                Is a Supplemental Form 8 attached?                                            YES/NO








                                                                                                          No





              
                Date of disclosure:                                              5 November 2025



              
                Contact name:                                                    Sandy Coombs, Alkermes



              
                Telephone number:                                                       +1 781 609 6377





              
                Public disclosures under Rule 8.1 of the Rules must be made to a
    Regulatory Information Service.

Ap12

NOTES ON FORM 8.1(a) and (b)

See the definition of "interest in a relevant security" in Rule 2.5 of Part A of the Rules and see Rule 8.6(a) of Part B of the Rules.
See the definition of "relevant securities" in Rule 2.1 of Part A of the Rules.
If details included in a disclosure under Rule 8 are incorrect, they should be corrected as soon as practicable in a subsequent disclosure. Such disclosure should state clearly that it corrects details disclosed previously, identify the disclosure or disclosures being corrected, and provide sufficient detail for the reader to understand the nature of the corrections. In the case of any doubt, the Panel should be consulted.

For full details of disclosure requirements, see Rule 8 of the Rules. If in doubt, consult the Panel.

References in these notes to "the Rules" are to the Irish Takeover Panel Act, 1997, Takeover Rules, 2022.

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